Jama 2013 calcium. Considerable controversy exists regarding the association between dietary calcium intake and risk of mortality from cardiovascular disease and all causes. In Mar 27, 2013 · Lamas et al report results of the Trial to Assess Chelation Therapy (TACT), a randomized controlled trial analyzing whether EDTA-based chelation therapy reduced cardiovascular events in 1708 patients with a history of myocardial infarction. The standard CAC score is the Agatston, which is weighted upward for greater calcium density. Unadjusted total calcium is the best method for measuring calcium in clinical practice, according to results of a study published in JAMA Network Open. Therefore, we performed a meta-analysis of prospective cohort studies to examine the controversy. When there is clinical concern for hypocalcemia, we should measure ionized calcium levels to guide further decision-making and management. Mar 13, 2013 · Adequate calcium intake is essential for bone health and proper function of other organ systems. These findings support current safety warnings regarding concurr … Jan 15, 2014 · Abstract Importance: Coronary artery calcium (CAC), measured by computed tomography (CT), has strong predictive value for incident cardiovascular disease (CVD) events. 2123. In editorials, Nissen and Bauchner et al discuss the May 15, 2025 · Many clinicians continue to use calcium correction formulas (based on their training experiences); however, multiple studies support discontinuation of this practice. Jan 21, 2025 · We identified adults (≥18 years of age) who were tested simultaneously (ie, same date and time) for serum total calcium and ionized calcium between January 1, 2013, and October 31, 2019. 2013. 2013 Mar 13;309 (10):972. Mar 13, 2013 · JAMA. In a multicenter, prospective, observational trial at 6 US sites, Criqui and colleagues study a diverse cohort of 3398 men and women, aged 45 to 84 years, to determine the independent associations of coronary artery calcium (CAC) volume and CAC density with incident cardiovascular disease events. 2 days ago · Stay up to date, maintain your CME with the latest research, author interviews, apps, and learning courses from JAMA and the Specialty Journals. . However, some data suggest increased plaque calcium density may be protective for CVD. doi: 10. “Correcting” calcium could lead to missed episodes of true hypocalcemia. Feb 18, 2025 · Albumin-adjusted calcium formulas did not outperform unadjusted total serum calcium in assessing calcium status. 1001/jama. Feb 4, 2013 · Objective To investigate whether intake of dietary and supplemental calcium is associated with mortality from total cardiovascular disease (CVD), heart disease, and cerebrovascular diseases. Jan 2, 2025 · In this cross-sectional study drawn from a contemporaneous population, there appeared to be heavy reliance on adjustment formulas for calcium in clinical practice with little gain but considerable risk of misclassification of true calcium status, especially in the presence of hypoalbuminemia. These … Dec 18, 2013 · Among older adults taking a calcium-channel blocker, concurrent use of clarithromycin compared with azithromycin was associated with a small but statistically significant greater 30-day risk of hospitalization with acute kidney injury. Apr 22, 2013 · Objective: To investigate whether intake of dietary and supplemental calcium is associated with mortality from total cardiovascular disease (CVD), heart disease, and cerebrovascular diseases. But a new study adds to emerging evidence that suggests excessive calcium intake may increase the risk of death from cardiovascular disease. tzfvhp7owll9kptwvavmpwnv9a9p4emjjx5c77ocby